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Scientists have a short while ago determined and succeeded in synthesizing conolidine, a normal compound that shows assure to be a powerful analgesic agent with a more favorable safety profile. Although the precise system of action continues to be elusive, it truly is presently postulated that conolidine may have several biologic targets. Presently

Conolidine’s analgesic consequences stem from its conversation with non-opioid pain pathways. As opposed to opioids, which bind to µ-opioid receptors inside the central anxious technique, conolidine modulates alternate molecular targets. A Science Innovations analyze identified that conolidine interacts with the atypical chemokine receptor ACKR3

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